Aurélien Marabelle MD, PhD
Clinical Director of Cancer Immunotherapy at the Gustave Roussy Institute
Dr. Florian Rieder
Dr. Gisli Jenkins
Professor of Experimental Medicine, Faculty of Medicine & Health Sciences University of Nottingham
RXC004 clinical investigators
Aurélien Marabelle is the Clinical Director of the Cancer Immunotherapy Program at Gustave Roussy Cancer Center in Villejuif, France. Dr Marabelle’s clinical practice is dedicated to Early Phase Clinical trials in Cancer Immunotherapy and his translational research is focused on mechanisms of action of immune checkpoint monoclonal antibodies. He works as a senior medical oncologist and an investigator in the Drug Development Department (DITEP) directed by Prof Jean-Charles Soria. He is coordinating a team focusing on cancer immunotherapy translational research projects in the INSERM U1015 lab directed by Prof Laurence Zitvogel. Dr Marabelle is a member of ESMO, ASCO, EATI & AACR.
Florian Rieder, MD, received his medical degree from the Ludwig-Maximilians-University Medical School in Munich, Germany. He underwent training in Internal Medicine / Gastroenterology at the Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg, Germany and a residency in Internal Medicine and fellowship in Gastroenterology, Hepatology and Nutrition at the Cleveland Clinic in Cleveland, Ohio. Dr. Rieder has performed a research fellowships at Harvard Medical School and the Cleveland Clinic.
Dr. Rieder is an investigator at the Department of Inflammation and Immunity and an Associate Staff at the Department of Gastroenterology, Hepatology and Nutrition at the Cleveland Clinic, Cleveland. His clinical focus is patients with inflammatory bowel diseases (IBD) with a special emphasis on the field of pathogenesis, prediction and
therapy of IBD.
Dr. Rieder has published more than 70 articles and book chapters and has been recognized for his expertise as indicated through invitations to the steering committee of the 2 nd European Crohn’s and Colitis Organization (ECCO) scientific workshop on ‘Intestinal healing’, group leader of the 4 th ECCO scientific workshop on ‘Intestinal fibrosis’, invitations as a full member of the consensus panel of the ECCO guidelines on Crohn’s disease, lead author of the ECCO guidelines on Ulcerative colitis and lead author of the first ECCO clinical consensus on ‘Diagnosis and Management of Intestinal Fibrosis’ as well as multiple international invitations as a speaker, session chair or conference faculty.
Dr. Rieder serves as an abstract reviewer for all major GI conferences, he is an associate editor (Clinical and Translational Gastroenterology) and on several editorial boards of medical journals (Journal of Crohn’s and Colitis, Inflammatory Bowel Diseases, Gastroenterology and Hepatology, Fibrogenesis and Tissue Repair, American Journal of Physiology Gastrointestinal and Liver Physiology). He is proud of his significant ties to the ECCO, which he served as the chair of Y-ECCO, member of the ECCO operational board and prior Y-ECCO committee member and currently member of the scientific committee. He is currently chair of REACH-IBD and is a member of the Professional Education Committee of the Crohn’s and Colitis Foundation.
Dr Jenkins’ research focuses on the mechanism by which injury leads to scarring in the lung. Lung scarring is the central process leading to disability and death in people with Idiopathic Pulmonary Fibrosis, and also occurs in diseases such as chronic asthma where it promotes airway remodelling and impaired lung function. Following injury to the lung various cells activate TGFb via integrins in a spatially restricted manner. The activated TGFb then leads to cellular changes that promote the development of scarring. Much of the work is focused on two integrins in two cell types within the lung.
Dr. Natalie Cook, Senior Clinical Lecturer in Experimental Cancer Medicine and Honorary Consultant, Christie Hospital, Manchester, England. More information.
Professor Sarah P Blagden, Associate Professor of Experimental Cancer Medicines & Consultant Medical Oncologist/ Director of Early Phase Cancer trails unit & Oxford ECMC lead, University of Oxford, Department of Oncology, England. More information.
Professor Ruth Plumber, Clinical Professor of Experimental Cancer Medicine, Northern Institute of Cancer Research, Newcastle University, England. More information.
Dr. Debashis Sarker, Senior Lecturer and Honorary Consultant in Medical Oncology, King’s College Hospital & Guy’s and St Thomas hospital, London, England. More information
Dr. Juanita Lopez, Consultant Medical Oncologist, Royal Marsden Hospital, Institute Cancer Research, Surrey, England. More Information