Permanent Position – Senior Scientist, Redx Biology

Closing date: 17-Feb-2023

Redx Pharma is a clinical-stage biotechnology company focused on the discovery and development of novel, small molecule, highly targeted medicines for the treatment of cancer and fibrotic diseases. The Company has a strong track record of discovering new drug candidates through its core strengths in medicinal chemistry and translational science. Redx’s lead oncology product candidate, the Porcupine inhibitor RXC004, being developed as a targeted treatment for Wnt-dependent cancers, is currently undertaking a Phase 2 programme as both a monotherapy and in combination with anti-PD-1. The Company’s lead fibrosis product candidate, the selective ROCK2 inhibitor RXC007, is in development for interstitial lung disease and commenced a Phase 2a trial for idiopathic pulmonary fibrosis in October 2022.  Redx’s third drug candidate, RXC008, a GI-targeted ROCK inhibitor for the treatment of fibrostenotic Crohn’s disease, is currently in pre-IND stage.

The Company’s accomplishments are evidenced not only by its two wholly-owned Phase 2 clinical-stage product candidates and rapidly expanding pipeline, but also by its strategic transactions, which include significant partnering deals with both AstraZeneca and Jazz Pharmaceuticals.

The Role:

Redx requires a highly motivated laboratory-based senior scientist with substantial previous lab experience and a willingness to learn new techniques. The successful applicant will contribute to the discovery of novel pharmaceuticals by providing scientific and technical input for the delivery of our exciting research programmes.

Responsibilities include:

  • Independently undertaking experiments and interpreting results to deliver a significant high-quality data for projects.
  • Identifying and establishing novel in vitro biological assays and techniques to meet the requirements of projects. Troubleshooting and resolving assay problems.
  • Building the company’s general technical capabilities and helping to accelerate the delivery of project milestones.
  • Prioritising and delivering your workload effectively to meet the needs/timelines of the project.
  • Working with different people and project teams to help deliver the company research goals.
  • Applying a high attention to detail and maintaining good experimental records in electronic lab notebook.
  • Adhering to all company safety procedures.
  • Identifying and evaluating new areas of research or potential drug discovery targets to expand the scope of the company’s research portfolio.
  • Maintaining awareness of contemporary drug discovery and highlighting new developments, insights and lessons learned throughout the organisation.
  • Developing scientific strategy and technical functionalities for projects, and effectively communicating this across the organisation.
  • Establishing and/or managing external collaborations with universities, CROs or commercial partners.
  • Presenting science to potential external collaborators/partners as required.

The successful candidate will:

  • Have demonstrated evidence of excellent in vitro laboratory skills.
  • Be able to show innovation and creativity; flexibility and adaptability; resilience and the ability to make appropriate decisions with support from their line manager.
  • Preferably have a PhD with at least 2 years of relevant industrial experience, or have an MSc/BSc with greater than 4 years of drug discovery experience. Research knowledge in the areas of Fibrosis, Immunology and/or Oncology is a key advantage.
  • Have extensive practical experience of techniques commonly used in bioscience research, such as biochemical assays, cell culture, flow cytometry, ELISA and RT-PCR
  • Ideally be available to start in March 2023.

What we offer:

In return, Redx will offer you the opportunity to work as part of a dynamic team at an exciting drug discovery company where you will get exposure to a broad range of activities, drive novel pharmaceuticals towards the clinic, and develop your drug discovery skills.

The closing date for applications is Friday, 17th February 2023.

Pinterest LinkedIn